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there is just enough insulin secreted to help glucose di use out of the bloodstream, and into the target cells, so that a condition of normoglycemia (NORmoh-gleye-SEE-me-uh) prevails Normoglycemia is a blood condition of (-emia) normal (normo-) sweetness or glucose (glyc) When the pancreas (and its beta cells) are of a normal size and activity level, then there is a normosecretion of insulin, and a resulting state of normoglycemia within the bloodstream (see Figure 156, A) What happens if a gland atrophies (AH-troh-fees) shrinks in size or some of its cells die or are removed Since just a shrunken mass of epithelial cells is left alive and functioning, gland hyposecretion (HIGH-poh-seeKREE-shun) results (see Figure 156, B) Hyposecretion is literally a condition of de cient or below normal (hypo-) secretion of some particular hormone To illustrate, consider what happens if many of the beta cells become damaged or die, due either to genetic mutations or to an overall atrophy of the pancreas One serious disease that could result is diabetes (die-uh-BEEteez) mellitus (MEL-uh-tus) Diabetes mellitus exactly translates to mean a honey-sweet (mellit) passing through (diabetes) of urine from the body Persons su ering with Diabetes mellitus often have beta cells that do not produce enough normal insulin to signi cantly reduce the blood glucose level As a result of such long-term hyposecretion of insulin, too much glucose is left behind in the bloodstream After glucose builds up over time, a state of hyperglycemia (HIGH-pergleye-SEE-mee-ah) follows Hyperglycemia is an excessive or above normal (hyper-) concentration of glucose within the bloodstream With so much glucose staying in the blood, eventually some of it is excreted into the urine by the kidneys The result is technically called glycosuria (gleyekoh-SUR-ee-ah) or an abnormal condition of (-ia) glucose (glycos) within the urine (ur) Finally, let us ponder the condition of glandular hypertrophy (enlargement) or the presence of gland tumors (Figure 156, C) With so many additional epithelial cells being present, the enlarged gland often has a hypersecretion (HIGH-per-see-KREE-shun) of its hormones This means, of course, that there is an excessive or above normal rate of hormone secretion by the gland Extreme physiological results often occur Let us apply this to the pancreas and its secretion of insulin When there is a marked enlargement (hypertrophy) of the pancreas and its beta cells, then there is also a marked hypersecretion of insulin Too much glucose is removed from the bloodstream and transported into the body target cells With so much glucose gone, severe hypoglycemia (HIGH-poh-gleye-SEEmee-ah) may occur [Study suggestion: Following the pattern set by the pre-.

Blood normoglycemia Hyposecretion of insulin (B) ATROPHY (SHRINKAGE) OF PANCREAS Blood hyperglycemia Hypersecretion of insulin Blood hypoglycemia (C) HYPERTROPHY OF PANCREAS

Another area the surveys were interested in determining were the plans for corporate users in the top 500 companies to implement wireless Web access The survey looked at a time frame of 2 years The results of that inquiry are shown in Figure 11-6

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ceding paragraphs, try to write the literal English translation of hypoglycemia on a piece of paper Check your translation with a friend] Insulin shock or coma can result from a severe and prolonged hypoglycemia The neurons in the brain are completely starved of glucose, their major fuel The person goes into coma or the deep sleep of brain failure, and may lose consciousness and die

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Refer to the text in this chapter if necessary A good score is at least 8 correct answers out of these 10 questions The answers are listed in the back of this book 1 A synapse represents: (a) A place where the tips of an axon almost touch a muscle ber (b) The major central region of a neuron (c) The uid- lled gap where two neurons nearly come together (d) A traveling wave of chemical excitation _____ are masses of epithelial cells specialized for the function of secretion: (a) Blood vessels (b) Hormones (c) Hormone-binding sites (d) Glands The mammary (MAH-mair-ee) glands within the female breasts are most accurately classi ed as: (a) Synapses (b) Chemical messengers (c) Endocrine glands (d) Exocrine glands The phrase neuroendocrine system implies that: (a) Some parts of the nervous system have no relationship to body secretions (b) There are just too darn many body structures and functions to memorize! (c) Some nervous structures and endocrine gland structures are functionally related (d) Certain glands have unknown body functions that the brain can t understand Antidiuretic hormone is actually produced and secreted by the: (a) Posterior pituitary (b) Anterior pituitary (c) Entire pituitary body (d) Hypothalamus

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